Rampage 2: Universal Tour
The players choose one of the three original monsters to rescue. The player then places the characters in the part of the world where the rescue takes place. They work as a collective to destroy buildings, eat people, and destroy cars, which leads to competition between players. When a player unlocks (literally) George, Lizzie or Ralph, they become playable characters. Once all the monsters are rescued, aliens invade Earth and the monsters are the only ones who can save the planet they just partially destroyed. After fending off the invasion on Earth, the monsters rescue Myukus (a Cyclops-like alien) from Area 51 before chasing the aliens through space, destroying their bases throughout the solar system, and finally rampaging through their homeworld.
Story
George, Lizzie and Ralph have been captured and locked up for all the world to see. George is being held captive in New York City, Lizzie is locked up in Tokyo, and Ralph is being kept in London (a reference to King Kong, Godzilla, and Werewolf of London (or An American Werewolf in London). However, Scumlabs, who have just rebuilt their facilities in Salt Lake City, cause another accident that produces three new monsters: Boris, a rhinoceros, Curtis, a mouse, and Ruby, a lobster.